BDBM523613 US11136311, Compound 102

SMILES CC(C)CCc1c(Nc2nccc(n2)-c2cc3c(NC[C@]3(C)CO)c(c2)C#N)cnn1CCC(C)C

InChI Key InChIKey=KSXZKUXDFMJDLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523613   

TargetMitogen-activated protein kinase kinase kinase 14(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM523613(US11136311, Compound 102)
Affinity DataIC50: 2.20nMAssay Description:NIK/MAP3K14 auto-phosphorylation activity was measured using the AlphaScreen (αscreen) format (Perkin Elmer). All compounds tested were dissolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent