BDBM523249 (1r,4r)-N-(5- hydroxy- pyridin-2-yl)- 4-phenyl- cyclohexane- 1- carboxamide::US11135207, Example 28

SMILES Oc1ccc(NC(=O)[C@H]2CC[C@@H](CC2)c2ccccc2)nc1

InChI Key InChIKey=ONASJFJQNQGCSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523249   

TargetSphingolipid delta(4)-desaturase DES1(Human)
Centaurus Therapeutics

US Patent
LigandPNGBDBM523249(US11135207, Example 28 | (1r,4r)-N-(5- hydroxy- py...)
Affinity DataIC50: 5nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent