BDBM523230 (E)-N-(4- hydroxy- phenyl)-3- phenylbut-2- enamide::US11135207, Example 3

SMILES C\C(=C/C(=O)Nc1ccc(O)cc1)c1ccccc1

InChI Key InChIKey=AEGWAIBOKQWYKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 523230   

TargetSphingolipid delta(4)-desaturase DES1(Human)
Centaurus Therapeutics

US Patent
LigandPNGBDBM523230(US11135207, Example 3 | (E)-N-(4- hydroxy- phenyl)...)
Affinity DataIC50: 4.46E+3nMAssay Description:Jurkat clone E6-1 cells were grown and then seeded at 106 cells/mL in a 96-well plate (400 μL in each well. The cells were administered 100 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details
Go to US Patent