BDBM523221 US11161864, Example 37A::US11161864, Example 37B

SMILES NC(=O)c1cnc2n3CCOP(S)(=O)OC[C@H]4O[C@H]([C@H](OP(S)(=O)OCc3nc2c1)[C@@H]4F)n1cnc2c1nc(N)[nH]c2=O

InChI Key InChIKey=HTTYTSAFFGEUGH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 523221   

TargetStimulator of interferon genes protein(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523221(US11161864, Example 37A | US11161864, Example 37B)
Affinity DataIC50: 1.00E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [155-379](Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523221(US11161864, Example 37A | US11161864, Example 37B)
Affinity DataIC50: 1.00E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523221(US11161864, Example 37A | US11161864, Example 37B)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523221(US11161864, Example 37A | US11161864, Example 37B)
Affinity DataIC50: 1.00E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [155-379](Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523221(US11161864, Example 37A | US11161864, Example 37B)
Affinity DataIC50: 1.00E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523221(US11161864, Example 37A | US11161864, Example 37B)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent