BDBM523191 US11161864, Example 16A

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1O[C@@H]2COP(S)(=O)OCCn3nc(nc3COP(S)(=O)O[C@@H]1[C@@H]2F)-c1cncs1

InChI Key InChIKey=CGZKSKVWBBXSSR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 523191   

TargetStimulator of interferon genes protein(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523191(US11161864, Example 16A)
Affinity DataIC50: 5.50E+4nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [155-379](Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523191(US11161864, Example 16A)
Affinity DataIC50: 5.50E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523191(US11161864, Example 16A)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent