BDBM523187 US11161864, Example 11D

SMILES Cc1ncc2nc3COP(S)(=O)O[C@@H]4[C@@H](F)[C@@H](COP(S)(=O)OCCn3c2n1)O[C@H]4n1cnc2c1nc(N)[nH]c2=O

InChI Key InChIKey=AWORAOZZDAZIAQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 523187   

TargetStimulator of interferon genes protein(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523187(US11161864, Example 11D)
Affinity DataIC50: 5.50E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [155-379](Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523187(US11161864, Example 11D)
Affinity DataIC50: 1.00E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523187(US11161864, Example 11D)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent