BDBM523152 US11161864, Example 6B

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1O[C@@H]2COP(S)(=O)OCCn3c(COP(O)(=O)O[C@@H]1[C@H]2F)nc1cncnc31

InChI Key InChIKey=ZLOGXSPWBRPFLC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 523152   

TargetStimulator of interferon genes protein(Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523152(US11161864, Example 6B)
Affinity DataIC50: 1.00E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [155-379](Human)
Venenum Biodesign

US Patent
LigandPNGBDBM523152(US11161864, Example 6B)
Affinity DataIC50: 1.00E+3nMAssay Description:A human STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was utilized to detect binding of compounds to STING pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein [154-378](Mouse)
Venenum Biodesign

US Patent
LigandPNGBDBM523152(US11161864, Example 6B)
Affinity DataIC50: 1.00E+3nMAssay Description:The murine STING [3H] 2′,3′-cGAMP scintillation proximity competition binding assay was performed in the same manner as the human STING c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent