BDBM523002 1-(4-(4-amino-7-(1- methylpiperidin-4-yl)- 7H-pyrrolo[2,3- d]pyrimidin-5-yl)-2- fluorophenyl)-3-(3-(1- (trifluoromethyl)cyclopropyl)isoxazol- 5-yl)urea::US11161852, Compound 26::US11713321, Example 26

SMILES CN1CCC(CC1)n1cc(-c2ccc(NC(=O)Nc3cc(no3)C3(CC3)C(F)(F)F)c(F)c2)c2c(N)ncnc12

InChI Key InChIKey=ULGNGAPMENHMIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 523002   

TargetSerine/threonine-protein kinase Nek7(Human)
Halia Therapeutics

US Patent
LigandPNGBDBM523002(US11161852, Compound 26 | 1-(4-(4-amino-7-(1- meth...)
Affinity DataIC50: 400nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and a caseins, obtained from Sigma Aldrich, c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase Nek7(Human)
Halia Therapeutics

US Patent
LigandPNGBDBM523002(US11161852, Compound 26 | 1-(4-(4-amino-7-(1- meth...)
Affinity DataIC50: 400nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and κ caseins, obtained from Sigma Aldri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
Go to US Patent