BDBM522990 1-(4-(4-amino-7- cyclopropyl-7H- pyrrolo[2,3- d]pyrimidin-5- yl)phenyl)-3-(3-(tert- butyl)isoxazol-5- yl)urea::US11161852, Compound 13::US11713321, Example 13

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cn(C3CC3)c3ncnc(N)c23)on1

InChI Key InChIKey=ROKRFQWVHAGBME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522990   

TargetSerine/threonine-protein kinase Nek7(Human)
Halia Therapeutics

US Patent
LigandPNGBDBM522990(US11161852, Compound 13 | 1-(4-(4-amino-7- cyclopr...)
Affinity DataIC50: 400nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and a caseins, obtained from Sigma Aldrich, c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase Nek7(Human)
Halia Therapeutics

US Patent
LigandPNGBDBM522990(US11161852, Compound 13 | 1-(4-(4-amino-7- cyclopr...)
Affinity DataIC50: 400nMAssay Description:Casein substrate (from bovine milk, hydrolyzed and partially dephosphorylated mixture of α, β and κ caseins, obtained from Sigma Aldri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2023
Entry Details
Go to US Patent