BDBM522523 2-(2-isopropylpyridin-3-yl)-9-::US11161848, Compound I-412::US11161848, Compound I-81

SMILES CC(C)c1ncccc1-c1ncc2CC(=O)N(Cc3ccc(cc3)-c3nc(cn3C)C(F)(F)F)c2n1

InChI Key InChIKey=SVDGGZQASWVDQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522523   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM522523(US11161848, Compound I-81 | 2-(2-isopropylpyridin-...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM522523(US11161848, Compound I-81 | 2-(2-isopropylpyridin-...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent