BDBM522486 2-(1-methyl-1H-indazol-7-yl)-::US11161848, Compound I-44

SMILES Cn1cc(nc1-c1ccc(CN2C(=O)Cc3cnc(nc23)-c2cccc3cnn(C)c23)cc1)C(F)(F)F

InChI Key InChIKey=KHRAFSGCMUFAJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 522486   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM522486(US11161848, Compound I-44 | 2-(1-methyl-1H-indazol...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent