BDBM522475 2-(2-cyclopropylpyridin-3-yl)-::US11161848, Compound I-33

SMILES FC(F)(F)c1cn(C2COC2)c(n1)-c1ccc(CN2C(=O)Cc3cnc(nc23)-c2cccnc2C2CC2)cc1

InChI Key InChIKey=OOFQHDZEYHPCKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 522475   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM522475(US11161848, Compound I-33 | 2-(2-cyclopropylpyridi...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent