BDBM522443 9-(4-(3,5-dimethyl-1H-::US11161848, Compound I-1::US11161848, Compound I-212::US11161848, Compound I-213

SMILES CC(C)c1ccccc1-c1ncc2CC(=O)N(Cc3ccc(cc3)-n3nc(C)cc3C)c2n1

InChI Key InChIKey=YKABPPQPHVIEEJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 522443   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM522443(9-(4-(3,5-dimethyl-1H- | US11161848, Compound I-21...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM522443(9-(4-(3,5-dimethyl-1H- | US11161848, Compound I-21...)
Affinity DataIC50: 50nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Forma Therapeutics

US Patent
LigandPNGBDBM522443(9-(4-(3,5-dimethyl-1H- | US11161848, Compound I-21...)
Affinity DataIC50: 1.10E+3nMAssay Description:The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent