BDBM522415 8-fluoro-2-(cis-3-fluoro-3-methylcyclobutyl)-1- [(2R,4R)-2-methyltetrahydro-2H-pyran-4-yl]-1H- imidazo[-c]quinoline::US11161844, Example 31

SMILES C[C@@H]1CC(CCO1)n1c(nc2cnc3ccc(F)cc3c12)C1C[C@@](C)(F)C1

InChI Key InChIKey=BZUONQULAOIALH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522415   

LigandPNGBDBM522415(US11161844, Example 31 | 8-fluoro-2-(cis-3-fluoro-...)
Affinity DataIC50: 22nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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LigandPNGBDBM522415(US11161844, Example 31 | 8-fluoro-2-(cis-3-fluoro-...)
Affinity DataIC50: 15.8nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent