BDBM522414 US11161844, Example 30::[cis-4-{8-chloro-2-[(3R)-tetrahydrofuran-3-yl]-1H-imidazo[-c]quinolin-1-yl}tetrahydro-2H-pyran-2-yl]acetonitrile, DIAST 1

SMILES Clc1ccc2ncc3nc([C@H]4CCOC4)n(C4CCOC(CC#N)C4)c3c2c1

InChI Key InChIKey=AHQPJCUEBFHSCN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522414   

LigandPNGBDBM522414(US11161844, Example 30 | [cis-4-{8-chloro-2-[(3R)-...)
Affinity DataIC50: 6.06nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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LigandPNGBDBM522414(US11161844, Example 30 | [cis-4-{8-chloro-2-[(3R)-...)
Affinity DataIC50: 3.02nMAssay Description:LRRK2 kinase activity was measured using Lantha Screen technology from Invitrogen. GST-tagged truncated LRRK2 from Invitrogen (Cat #PV4874) was incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent