BDBM522205 US11161839, Example 3a

SMILES CC(Nc1cc(=O)n(C)c2ccc(Nc3ccnc(Cl)c3C#N)cc12)C(=O)NCc1cnn(C)c1

InChI Key InChIKey=OMXNCIYGLQZOHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522205   

TargetB-cell lymphoma 6 protein [5-129](Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM522205(US11161839, Example 3a)
Affinity DataIC50: 117nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

TargetB-cell lymphoma 6 protein [5-129](Human)
The Institute of Cancer Research: Royal Cancer Hospital

US Patent
LigandPNGBDBM522205(US11161839, Example 3a)
Affinity DataIC50: 89.1nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent