BDBM522186 (S)-3-Amino-6-(2-(1- cyclopropylethyl)-7- (methylsulfonyl)-1- oxoisoindolin-5-yl)-N- isopropylpyrazine-2-carboxamide::US11161838, Example 4

SMILES CC(C)NC(=O)c1nc(cnc1N)-c1cc2CN([C@@H](C)C3CC3)C(=O)c2c(c1)S(C)(=O)=O

InChI Key InChIKey=ACKBSIHRAOXNBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522186   

LigandPNGBDBM522186((S)-3-Amino-6-(2-(1- cyclopropylethyl)-7- (methyls...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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LigandPNGBDBM522186((S)-3-Amino-6-(2-(1- cyclopropylethyl)-7- (methyls...)
Affinity DataIC50: 2.00E+3nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent