BDBM522182 (S)-3-Amino-6-(2-(1- cyclopropylethyl)-1- oxoisoindolin-5-yl)-N- isopropylpyrazine-2- carboxamide::US11161838, Example 2

SMILES CC(C)NC(=O)c1nc(cnc1N)-c1ccc2C(=O)N(Cc2c1)[C@@H](C)C1CC1

InChI Key InChIKey=LSSBFNLYYMLQQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522182   

LigandPNGBDBM522182((S)-3-Amino-6-(2-(1- cyclopropylethyl)-1- oxoisoin...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent

LigandPNGBDBM522182((S)-3-Amino-6-(2-(1- cyclopropylethyl)-1- oxoisoin...)
Affinity DataIC50: 2.00E+3nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent