BDBM522178 (S)-3-Amino-6-(2-(1-cyclopropylethyl)-1-oxoisoindolin-5-yl)-N-(tetrahydro-2H-pyran-4-yl)pyrazine-2-carboxamide trifluoroacetate salt::US11161838, Example 1

SMILES C[C@@H](C1CC1)N1Cc2cc(ccc2C1=O)-c1cnc(N)c(n1)C(=O)NC1CCOCC1

InChI Key InChIKey=RJFNEVPFTLXBDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522178   

LigandPNGBDBM522178((S)-3-Amino-6-(2-(1-cyclopropylethyl)-1-oxoisoindo...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
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LigandPNGBDBM522178((S)-3-Amino-6-(2-(1-cyclopropylethyl)-1-oxoisoindo...)
Affinity DataIC50: 2.00E+3nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2022
Entry Details
Go to US Patent