BDBM522047 N-[3-[6-(difluoromethoxy)-3- oxo-4H-1,4-benzoxazin-7-yl]- 1-methyl-pyrazol-4- yl]pyrazolo[1,5-a]pyrimidine- 3-carboxamide::US11155557, Example 137

SMILES Cn1cc(NC(=O)c2cnn3cccnc23)c(n1)-c1cc2OCC(=O)Nc2cc1OC(F)F

InChI Key InChIKey=HICJIUGQVXQINW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 522047   

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandPNGBDBM522047(US11155557, Example 137 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandPNGBDBM522047(US11155557, Example 137 | N-[3-[6-(difluoromethoxy...)
Affinity DataKi:  0.0900nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent