BDBM521868 US11155546, Compound G-42

SMILES CC1CCC(CN1C(=O)C=C)Nc1nc(Nc2ccc(N3CCOCC3C)c(F)c2)c2C(=O)NCc2c1F

InChI Key InChIKey=PMUOPDUCKDBXJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521868   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521868(US11155546, Compound G-42)
Affinity DataIC50: 5nMAssay Description:BTK: The compound was predissolved in 100% DMSO. 10 mM drug stock solution was obtained by dissolution at room temperature and then serially diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521868(US11155546, Compound G-42)
Affinity DataIC50: 5.19E+3nMAssay Description:EGFR: The working concentration of each component in 10 μl wild-type EGFR kinase reaction system was: 10 μM ATP, 0.8 ng/μl wild-type E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent