BDBM521850 US11155546, Compound G-17

SMILES Fc1c2CNC(=O)c2c(Nc2ccc(cc2)N2CCOCC2=O)nc1NC1CCCN(C1)C(=O)C=C

InChI Key InChIKey=OWOZUFOTJMDPGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521850   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521850(US11155546, Compound G-17)
Affinity DataIC50: 2nMAssay Description:BTK: The compound was predissolved in 100% DMSO. 10 mM drug stock solution was obtained by dissolution at room temperature and then serially diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetEpidermal growth factor receptor(Human)
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521850(US11155546, Compound G-17)
Affinity DataIC50: 1.50E+3nMAssay Description:EGFR: The working concentration of each component in 10 μl wild-type EGFR kinase reaction system was: 10 μM ATP, 0.8 ng/μl wild-type E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent