BDBM521839 US11155546, Compound G-4

SMILES COCCOc1ccc(Nc2nc(NC3CCCN(CC3)C(=O)C=C)c(F)c3CNC(=O)c23)cc1

InChI Key InChIKey=SGGZDKRHWPACSX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521839   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521839(US11155546, Compound G-4)
Affinity DataIC50: 7nMAssay Description:BTK: The compound was predissolved in 100% DMSO. 10 mM drug stock solution was obtained by dissolution at room temperature and then serially diluted ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetEpidermal growth factor receptor(Human)
Shanghai Haiyan Pharmaceutical Technology

US Patent
LigandPNGBDBM521839(US11155546, Compound G-4)
Affinity DataIC50: 2.37E+3nMAssay Description:EGFR: The working concentration of each component in 10 μl wild-type EGFR kinase reaction system was: 10 μM ATP, 0.8 ng/μl wild-type E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent