BDBM521798 US11155544, Compound 25

SMILES Cc1cc(Oc2ccccc2)ccc1-c1nn([C@@H]2CCCN(C2)C(=O)C(=CC(C)(C)N2CCN(CC2)C2COC2)C#N)c2ccnc(N)c12

InChI Key InChIKey=NDIMIMKKLBAREE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 521798   

TargetTyrosine-protein kinase BTK(Human)
Principia Biopharma

US Patent
LigandPNGBDBM521798(US11155544, Compound 25)
Affinity DataIC50: 4.40nMAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of BTK kinase activity of a compound of the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent