BDBM521445 N-(1-(1- ((5,6- Dichloro-1H- indol-2-yl) methyl)-1,8- diazaspiro [4.5]decane- 8-carbonyl)- 1H-pyrazol-3- yl)acetamide::US11149037, Example 43

SMILES CC(=O)Nc1ccn(n1)C(=O)N1CCC2(CCCN2Cc2cc3cc(Cl)c(Cl)cc3[nH]2)CC1

InChI Key InChIKey=AYKLXYIJBSAABL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521445   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM521445(N-(1-(1- ((5,6- Dichloro-1H- indol-2-yl) methyl)-1...)
Affinity DataIC50: 100nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
H. Lundbeck

US Patent
LigandPNGBDBM521445(N-(1-(1- ((5,6- Dichloro-1H- indol-2-yl) methyl)-1...)
Affinity DataIC50: 5.50E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or PC3 cell membrane fractions for human assays) (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
US Patent