BDBM521117 N-{3-[3-(4-Chlorophenyl)-1-{[1-(3-chloropyridin-2-yl)-1H-1,2,4-triazol-3-yl]methyl}-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]-1,1,1-trifluoropropan-2-yl}-3,3,3-trifluoropropanamide (Racemate)::US11149023, Example 11

SMILES FC(F)(F)CC(=O)NC(Cn1c(nn(Cc2ncn(n2)-c2ncccc2Cl)c1=O)-c1ccc(Cl)cc1)C(F)(F)F

InChI Key InChIKey=HKNSUPCHOJIVAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521117   

TargetVasopressin V1a receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM521117(N-{3-[3-(4-Chlorophenyl)-1-{[1-(3-chloropyridin-2-...)
Affinity DataIC50: 1.20nMAssay Description:The identification of agonists and antagonists of the V1a and V2 vasopressin receptors from humans, rats and dogs as well as the quantification of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetVasopressin V2 receptor(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM521117(N-{3-[3-(4-Chlorophenyl)-1-{[1-(3-chloropyridin-2-...)
Affinity DataIC50: 45.5nMAssay Description:The identification of agonists and antagonists of the V1a and V2 vasopressin receptors from humans, rats and dogs as well as the quantification of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent