BDBM521054 US11149020, Compound 55 (MW-063)

SMILES CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1cccc2c(F)cccc12

InChI Key InChIKey=PXBIXLVYZOIUHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521054   

TargetMitogen-activated protein kinase 14(Human)
Columbia University

US Patent
LigandPNGBDBM521054(US11149020, Compound 55 (MW-063))
Affinity DataIC50: 526nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
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TargetCasein kinase I isoform delta(Human)
Columbia University

US Patent
LigandPNGBDBM521054(US11149020, Compound 55 (MW-063))
Affinity DataIC50: 3.25E+4nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent