BDBM521046 US11149020, Compound 37 (MW-149)

SMILES CN1CCN(CC1)c1cc(-c2ccncc2F)c(nn1)-c1ccc2ccccc2c1

InChI Key InChIKey=RTXOYOLFTUOQAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521046   

TargetMitogen-activated protein kinase 14(Human)
Columbia University

US Patent
LigandPNGBDBM521046(US11149020, Compound 37 (MW-149))
Affinity DataIC50: 235nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetCasein kinase I isoform delta(Human)
Columbia University

US Patent
LigandPNGBDBM521046(US11149020, Compound 37 (MW-149))
Affinity DataIC50: 4.62E+3nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent