BDBM521025 US11149020, Compound 16 (MW-200)

SMILES CNc1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1

InChI Key InChIKey=QVSPCXIGISPFTI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 521025   

TargetMitogen-activated protein kinase 14(Human)
Columbia University

US Patent
LigandPNGBDBM521025(US11149020, Compound 16 (MW-200))
Affinity DataIC50: 175nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetCasein kinase I isoform delta(Human)
Columbia University

US Patent
LigandPNGBDBM521025(US11149020, Compound 16 (MW-200))
Affinity DataIC50: 4.98E+3nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Columbia University

US Patent
LigandPNGBDBM521025(US11149020, Compound 16 (MW-200))
Affinity DataKi:  100nMAssay Description:The concentration dependent ability of compounds to inhibit human p38α MAPK, p38β MAPK and CK-1δ were done essentially as described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2022
Entry Details
Go to US Patent