BDBM520672 US11149006, Compound I::US11149006, Compound IV

SMILES COc1ccc(cc1CN[C@H]1CCCN[C@H]1c1ccccc1)S(F)(F)(F)(F)F

InChI Key InChIKey=GUZFXBPYWSZXJQ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 520672   

TargetSubstance-P receptor(Human)
Xwpharma

US Patent
LigandPNGBDBM520672(US11149006, Compound IV | US11149006, Compound I)
Affinity DataIC50: 6.15nMAssay Description:Experimental procedure for NK-1, NK-2 and NK-3 calcium flux FLIPR assay: Perform the assay in the following steps: 1) Cell preparation: thaw each cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
Go to US Patent

TargetSubstance-P receptor(Human)
Xwpharma

US Patent
LigandPNGBDBM520672(US11149006, Compound IV | US11149006, Compound I)
Affinity DataIC50: 22.2nMAssay Description:Experimental procedure for NK-1, NK-2 and NK-3 calcium flux FLIPR assay: Perform the assay in the following steps: 1) Cell preparation: thaw each cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Xwpharma

US Patent
LigandPNGBDBM520672(US11149006, Compound IV | US11149006, Compound I)
Affinity DataIC50: 1.00E+4nMAssay Description:Experimental procedure for NK-1, NK-2 and NK-3 calcium flux FLIPR assay: Perform the assay in the following steps: 1) Cell preparation: thaw each cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
Go to US Patent

TargetSubstance-K receptor(Human)
Xwpharma

US Patent
LigandPNGBDBM520672(US11149006, Compound IV | US11149006, Compound I)
Affinity DataIC50: 1.00E+4nMAssay Description:Experimental procedure for NK-1, NK-2 and NK-3 calcium flux FLIPR assay: Perform the assay in the following steps: 1) Cell preparation: thaw each cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Xwpharma

US Patent
LigandPNGBDBM520672(US11149006, Compound IV | US11149006, Compound I)
Affinity DataIC50: 1.00E+4nMAssay Description:Experimental procedure for NK-1, NK-2 and NK-3 calcium flux FLIPR assay: Perform the assay in the following steps: 1) Cell preparation: thaw each cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
Go to US Patent

TargetNeuromedin-K receptor(Human)
Xwpharma

US Patent
LigandPNGBDBM520672(US11149006, Compound IV | US11149006, Compound I)
Affinity DataIC50: 1.00E+4nMAssay Description:Experimental procedure for NK-1, NK-2 and NK-3 calcium flux FLIPR assay: Perform the assay in the following steps: 1) Cell preparation: thaw each cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
Go to US Patent

TargetSubstance-P receptor(Human)
Xwpharma

US Patent
LigandPNGBDBM520672(US11149006, Compound IV | US11149006, Compound I)
Affinity DataIC50: 0.640nMAssay Description:Experimental procedure for competitive binding (Ki determination): Perform CisBio's Tag-Lite Tachykinin NK-1 binding assay according to manufactu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
Go to US Patent