BDBM520320 5-{3-Chloro-6-methoxy-2-methyl-5-[(1S)-1-(pyrido[3,2-d]pyrimidin-4-ylamino)ethyl]phenyl}-N,N-dimethylpyridine-2-carboxamide bis(trifluoroacetate)::US11130767, Example 3

SMILES COc1c(cc(Cl)c(C)c1-c1ccc(nc1)C(=O)N(C)C)[C@H](C)Nc1ncnc2cccnc12

InChI Key InChIKey=NTMOWLQSSMCYSZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520320   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte

US Patent

LigandBDBM520320(US11130767, Example 3 | 5-{3-Chloro-6-methoxy-2-me...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/8/2022
Entry Details
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