BDBM520315 4-{3-Chloro-6-ethoxy-2-fluoro-5-[1-(pyrido[3,2-d]pyrimidin-4-ylamino)ethyl]phenyl}pyrrolidin-2-one::US11130767, Example 2

SMILES CCOc1c(cc(Cl)c(F)c1C1CNC(=O)C1)C(C)Nc1ncnc2cccnc12

InChI Key InChIKey=OHUNNVMYBJGIPE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520315   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte

US Patent

LigandBDBM520315(US11130767, Example 2 | 4-{3-Chloro-6-ethoxy-2-flu...)Copy SMILESCopy InChI

Affinity DataIC50: 300nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/8/2022
Entry Details
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