BDBM520310 4-{3-Chloro-6-ethoxy-2-fluoro-5-[1-([1,3]thiazolo[5,4-d]pyrimidin-7-ylamino)ethyl]phenyl}pyrrolidin-2-one trifluoroacetate::US11130767, Example 1

SMILES CCOc1c(cc(Cl)c(F)c1C1CNC(=O)C1)C(C)Nc1ncnc2scnc12

InChI Key InChIKey=BZNWILKKCFATRF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520310   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Incyte

US Patent

LigandBDBM520310(US11130767, Example 1 | 4-{3-Chloro-6-ethoxy-2-flu...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/8/2022
Entry Details
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