BDBM520295 N-[(3S)-6′-Chloro-5-(cyclobutylmethyl)spiro[2,4-dihydro-1,5-benzoxazepine-3,1′-tetralin]-7-yl]sulfonylacetamide::US11130769, Ex. No. 12

SMILES CC(=O)NS(=O)(=O)c1ccc2OC[C@]3(CCCc4cc(Cl)ccc34)CN(CC3CCC3)c2c1

InChI Key InChIKey=JXOAAMDUGAHKEB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520295   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM520295(US11130769, Ex. No. 12 | N-[(3S)-6′-Chloro-5...)
Affinity DataKi:  15.8nMAssay Description:The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent