BDBM520281 (4S)-3-(2-((3-(4,7-Dimethyl-1H-benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-7-fluoro-4-isopropylchroman-3-yl methylcarbamate::US11130750, Example 21A

SMILES CNC(=O)O[C@@]1(CCN(C)CCCc2nc3c(C)ccc(C)c3[nH]2)COc2cc(F)ccc2[C@@H]1C(C)C

InChI Key InChIKey=FBIMVMYXHNLFCQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520281   

TargetCytochrome P450 3A4(Human)
Cavion

US Patent
LigandPNGBDBM520281(US11130750, Example 21A | (4S)-3-(2-((3-(4,7-Dimet...)
Affinity DataIC50: 1.50E+4nMAssay Description:The CYP2D6 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Cavion

US Patent
LigandPNGBDBM520281(US11130750, Example 21A | (4S)-3-(2-((3-(4,7-Dimet...)
Affinity DataIC50: 3.00E+3nMAssay Description:The CYP3A4 inhibition assays were conducted using Human Liver Microsomes purchased from Invitrogen and designed to screen potential inhibitors of Cyt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent