BDBM520139 5-Cyanopyridin-3-yl 4- (5-chloro-2- (trifluoromethyl)benzyl) piperazine-1-carboxylate::US11129827, Example 43

SMILES FC(F)(F)c1ccc(Cl)cc1CN1CCN(CC1)C(=O)Oc1cncc(c1)C#N

InChI Key InChIKey=LNTNANBTFVXUFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520139   

TargetFatty-acid amide hydrolase 1(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM520139(US11129827, Example 43 | 5-Cyanopyridin-3-yl 4- (5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetMonoglyceride lipase(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM520139(US11129827, Example 43 | 5-Cyanopyridin-3-yl 4- (5...)
Affinity DataIC50: 1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent