BDBM520137 5- (Trifluoromethyl)pyridin- 3-yl 2-(2-chloro-3-(3- chlorophenoxy)benzyl)- 2,7- diazaspiro[3.5]nonane-7- carboxylate::US11129827, Example 40

SMILES FC(F)(F)c1cncc(OC(=O)N2CCC3(CN(Cc4cccc(Oc5cccc(Cl)c5)c4Cl)C3)CC2)c1

InChI Key InChIKey=UXKIDQJESOHJLY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520137   

TargetFatty-acid amide hydrolase 1(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM520137(US11129827, Example 40 | 5- (Trifluoromethyl)pyrid...)
Affinity DataIC50: 5.00E+4nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent

TargetMonoglyceride lipase(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM520137(US11129827, Example 40 | 5- (Trifluoromethyl)pyrid...)
Affinity DataIC50: 1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
Go to US Patent