BDBM520134 5-Carbamoylpyridin-3-yl 2-(3,4-dichlorobenzyl)- 2,8- diazaspiro[4.5]decane-8- carboxylate::US11129827, Example 36

SMILES NC(=O)c1cncc(OC(=O)N2CCC3(CCN(Cc4ccc(Cl)c(Cl)c4)C3)CC2)c1

InChI Key InChIKey=ZNVSAFLAXFWGEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520134   

TargetFatty-acid amide hydrolase 1(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM520134(US11129827, Example 36 | 5-Carbamoylpyridin-3-yl 2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM520134(US11129827, Example 36 | 5-Carbamoylpyridin-3-yl 2...)
Affinity DataIC50: 1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent