BDBM520127 5- (Trifluoromethyl)pyridin- 3-yl 2-(3-(pyrrolidine-1- carbonyl)phenoxy)-7- azaspiro[3.5]nonane-7- carboxylate::US11129827, Example 26

SMILES FC(F)(F)c1cncc(OC(=O)N2CCC3(CC(C3)Oc3cccc(c3)C(=O)N3CCCC3)CC2)c1

InChI Key InChIKey=KHMBXZGKDHSYME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520127   

TargetMonoglyceride lipase(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM520127(US11129827, Example 26 | 5- (Trifluoromethyl)pyrid...)
Affinity DataIC50: 1.00E+3nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent

TargetFatty-acid amide hydrolase 1(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM520127(US11129827, Example 26 | 5- (Trifluoromethyl)pyrid...)
Affinity DataIC50: 5.00E+4nMAssay Description:Proteomes (mouse brain membrane fraction or cell lysates for mouse assays; human prefrontal cortex or cell membrane fractions for human assays) (50 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2022
Entry Details
US Patent