BDBM520105 US11142535, Compound 22

SMILES ONOC(=O)CCCC(=O)N1CCN(CC1)c1ccc(Nc2nc(cn3ccnc23)-c2ccc3cn[nH]c3c2)cc1

InChI Key InChIKey=IMQNIOREZBJDRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520105   

TargetTyrosine-protein kinase SYK(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520105(US11142535, Compound 22)
Affinity DataIC50: 50nMAssay Description:Measure of SYK protein kinase activity was carried out by using the Caliper mobility shift assay. The compound was dissolved with DMSO and diluted wi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM520105(US11142535, Compound 22)
Affinity DataIC50: 500nMAssay Description:HDAC activity was measured by the Synergy MX Multi-Function Microplate Reader. The compounds were dissolved with DMSO, and transferred to a 384 well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent