BDBM520084 (R)-2-(6-cyano-1-(2-(2-ethoxy-5-fluoro-phenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl)-5-methy1 -2,4-dioxo-1,2-dihydrothiopheno[2,3-d]pyrimidin-3(4H)-yl)-2-methylpropionic acid::US11142531, Example 19

SMILES CCOc1ccc(F)cc1[C@H](Cn1c2sc(C#N)c(C)c2c(=O)n(c1=O)C(C)(C)C(O)=O)OC1CCOCC1

InChI Key InChIKey=PLGSJSFKULYSBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 520084   

TargetAcetyl-CoA carboxylase 1(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM520084((R)-2-(6-cyano-1-(2-(2-ethoxy-5-fluoro-phenyl)-2-(...)
Affinity DataIC50: 2.70nMAssay Description:The degree of inhibition of the enzymatic activity of recombinant human ACC1, ACC2 proteins under in-vitro conditions by the preferred compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM520084((R)-2-(6-cyano-1-(2-(2-ethoxy-5-fluoro-phenyl)-2-(...)
Affinity DataIC50: 6nMAssay Description:The degree of inhibition of the enzymatic activity of recombinant human ACC1, ACC2 proteins under in-vitro conditions by the preferred compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent