BDBM520048 (R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(4-(4-ethyl-1H-imidazol-2-yl) phenyl)-3-oxohexahydroimidazo[1,5-a]pyrazin-7(1H)-yl)methyl)-2-(thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate::US11142527, Example 109

SMILES CCc1c[nH]c(n1)-c1ccc(cc1)N1C[C@@H]2CN(CC3=C([C@@H](N=C(N3)c3nccs3)c3ccc(F)cc3Cl)C(=O)OC)CCN2C1=O

InChI Key InChIKey=IGKLUACWAUOVHR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520048   

TargetLarge envelope protein(HBV-D)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM520048((R)-methyl 4-(2-chloro-4-fluorophenyl)-6-(((S)-2-(...)
Affinity DataEC50:  12.4nMAssay Description:8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent