BDBM519796 US11142526, Example 11

SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2cc3c(Cl)cc(Cl)cc3[nH]2)CC1)C(F)(F)F

InChI Key InChIKey=FROVXHXLDZKYIK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519796   

TargetMonoglyceride lipase(Mouse)
H. Lundbeck

US Patent
LigandPNGBDBM519796(US11142526, Example 11)
Affinity DataIC50: 100nMAssay Description:Inhibitors were administered to wild-type C57B1/6J by oral gavage in a vehicle of polyethylene glycol. Each animal was sacrificed 4 h following admin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent