BDBM519574 US11142520, Example 29

SMILES Clc1ccc(SC2C(=O)CC(NC2=O)(c2ccsc2)c2ccc(cc2)N2CCOCC2)c(Cl)c1

InChI Key InChIKey=MPHRDYMCSSTOSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 519574   

TargetL-lactate dehydrogenase A chain(Human)
Arctic Pharma

US Patent
LigandPNGBDBM519574(US11142520, Example 29)
Affinity DataIC50: 7.50E+4nMAssay Description:The inhibitory properties of the compounds were investigated using a coupled enzyme assay that links the lactate dehydrogenase (LDH) reaction to the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent

TargetL-lactate dehydrogenase B chain(Human)
Arctic Pharma

US Patent
LigandPNGBDBM519574(US11142520, Example 29)
Affinity DataIC50: 1.00E+5nMAssay Description:The inhibitory properties of the compounds were investigated using a coupled enzyme assay that links the lactate dehydrogenase (LDH) reaction to the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
US Patent