BDBM519500 US11142507, Compound MFH-2-104-1

SMILES CC(C)(C)c1cnc(CSc2cnc(NC3CCCN(C3)C(=O)N3CCC(CC3)NC(=O)C=C)s2)o1

InChI Key InChIKey=GAYYZQYKXQJXQA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 519500   

TargetCyclin-dependent kinase 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM519500(US11142507, Compound MFH-2-104-1)
Affinity DataIC50: 174nMAssay Description:Jurkat cells were treated with DMSO or concentration of compound indicated. 6 hours after treatment, cells were washed and harvested by resuspending ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM519500(US11142507, Compound MFH-2-104-1)
Affinity DataIC50: 6.17E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 9(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM519500(US11142507, Compound MFH-2-104-1)
Affinity DataIC50: 182nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent