BDBM519409 (4S,5R)-4- (hydroxymethyl)- N-(isoquinolin-4- ylmethyl)-5-[3- methoxy-5- (trifluoromethyl) phenyl]-2-oxo- 1,3-oxazolidine- 3-carboxamide::US11141410, Example 55

SMILES COc1cc(cc(c1)C(F)(F)F)[C@H]1OC(=O)N([C@H]1CO)C(=O)NCc1cncc2ccccc12

InChI Key InChIKey=JSSOWHNEXNWQEP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 519409   

TargetN-acetylglucosamine-1-phosphotransferase subunits alpha/beta(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM519409((4S,5R)-4- (hydroxymethyl)- N-(isoquinolin-4- ylme...)
Affinity DataIC50: 200nMAssay Description:The TarO biochemical enzymatic assay is a liquid chromatography-mass spectroscopy (LC-MS) based end point assay that measures C55-P-P-GlcNAc (LIPID I...More data for this Ligand-Target Pair
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Date in BDB:
3/4/2022
Entry Details
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