BDBM518877 US11141403, Example 12::US11141403, Example 15::tert-butyl 3-(1-{3- [cyclohexyl(ethyl) amino]-3-oxopropyl}-5- fluoro-1H- benzimidazol-2- yl)piperidine-1- carboxylate

SMILES CCN(C1CCCCC1)C(=O)CCn1c(nc2cc(F)ccc12)C1CCCN(C1)C(=O)OC(C)(C)C

InChI Key InChIKey=QRFVFQWADMTWPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 518877   

TargetN-acetylglucosamine-1-phosphotransferase subunits alpha/beta(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM518877(tert-butyl 3-(1-{3- [cyclohexyl(ethyl) amino]-3-ox...)
Affinity DataIC50: 60nMAssay Description:The TarO biochemical enzymatic assay is a liquid chromatography-mass spectroscopy (LC-MS) based end point assay that measures C55-P-P-GlcNAc (LIPID I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent

TargetN-acetylglucosamine-1-phosphotransferase subunits alpha/beta(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM518877(tert-butyl 3-(1-{3- [cyclohexyl(ethyl) amino]-3-ox...)
Affinity DataIC50: 120nMAssay Description:The TarO biochemical enzymatic assay is a liquid chromatography-mass spectroscopy (LC-MS) based end point assay that measures C55-P-P-GlcNAc (LIPID I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2022
Entry Details
Go to US Patent