BDBM518723 US11124538, Compound 46

SMILES COC[C@]12CC[C@@](C)(O)C[C@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4cc5ccncc5n4)[C@@]3(C)CC[C@H]21

InChI Key InChIKey=ZZHBHKZIQGYADB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518723   

TargetGamma-aminobutyric acid type B receptor subunit 1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM518723(US11124538, Compound 46)
Affinity DataIC50: 30nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent