BDBM518703 7-(1-Isopropylpyrazol-4-yl)-2-[6-(4-isopropyl-1,2,4-triazol-3-yl)-2-pyridyl]-6-methyl-3,4-dihydroisoquinolin-1-one::US11117891, Example 1

SMILES CC(C)n1cc(cn1)-c1cc2C(=O)N(CCc2cc1C)c1cccc(n1)-c1nncn1C(C)C

InChI Key InChIKey=AOPPZKAHBLFQGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 518703   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Eli Lilly

US Patent
LigandPNGBDBM518703(US11117891, Example 1 | 7-(1-Isopropylpyrazol-4-yl...)
Affinity DataIC50: 3.60nMAssay Description:The assay is done using an ADP-Glo Kinase Assay Kit (Promega, Catalog #V9102) according to the manufacturer's protocol with the following modific...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent