BDBM518570 US11124523, Example (+)-8

SMILES Clc1cccc(CNCC[C@]2(CCO[C@]3(CCOC3)C2)c2ccccn2)c1

InChI Key InChIKey=ZNAVSUOMXGYIRE-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 518570   

TargetMu-type opioid receptor(Human)
TBA

US Patent
LigandPNGBDBM518570(US11124523, Example (+)-8)
Affinity DataEC50:  1.80nMAssay Description:The experiment was performed using a cAMP detection kit from Cisbio (Cisbio #62AM4PEJ).More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetCytochrome P450 1A2(Rat)
TBA

US Patent
LigandPNGBDBM518570(US11124523, Example (+)-8)
Affinity DataIC50: 5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetCytochrome P450 2C9(Human)
TBA

US Patent
LigandPNGBDBM518570(US11124523, Example (+)-8)
Affinity DataIC50: 5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetCytochrome P450 2C19(Human)
TBA

US Patent
LigandPNGBDBM518570(US11124523, Example (+)-8)
Affinity DataIC50: 5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetCytochrome P450 2D6(Human)
TBA

US Patent
LigandPNGBDBM518570(US11124523, Example (+)-8)
Affinity DataIC50: 1.73E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
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TargetCytochrome P450 3A4(Human)
TBA

US Patent
LigandPNGBDBM518570(US11124523, Example (+)-8)
Affinity DataIC50: 5.00E+4nMAssay Description:To test the inhibitory effects of the compounds of the present disclosure on different isoforms of human cytochrome P450 isoenzymesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2022
Entry Details
Go to US Patent